Biochemistry of Collagens Laminins and Elastin

This book PDF is perfect for those who love Science genre, written by Morten Karsdal and published by Academic Press which was released on 28 May 2019 with total hardcover pages 434. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Biochemistry of Collagens Laminins and Elastin books below.

Biochemistry of Collagens  Laminins and Elastin
Author : Morten Karsdal
File Size : 43,5 Mb
Publisher : Academic Press
Language : English
Release Date : 28 May 2019
ISBN : 9780128170694
Pages : 434 pages
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Biochemistry of Collagens Laminins and Elastin by Morten Karsdal Book PDF Summary

There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease. Provides an updated comprehensive introduction to collagen and structural proteins Gives insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation Includes seven new chapters, including one on how collagen biomarkers are used in clinical research to support drug development and in precision medicine Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states Proves the importance of proteins for collagen assembly, function, and durability

Biochemistry of Collagens  Laminins and Elastin

There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these

Get Book
Biochemistry of Collagens  Laminins and Elastin

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