Clinical Studies and Therapies in Parkinson s Disease

This book PDF is perfect for those who love Medical genre, written by Juan Segura-Aguilar and published by Academic Press which was released on 12 June 2021 with total hardcover pages 306. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Clinical Studies and Therapies in Parkinson s Disease books below.

Clinical Studies and Therapies in Parkinson s Disease
Author : Juan Segura-Aguilar
File Size : 47,6 Mb
Publisher : Academic Press
Language : English
Release Date : 12 June 2021
ISBN : 9780128221587
Pages : 306 pages
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Clinical Studies and Therapies in Parkinson s Disease by Juan Segura-Aguilar Book PDF Summary

More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson’s disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4–6 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for Parkinson’s disease, but these efforts have failed when attempting to transfer these successful results to preclinical studies. Although several publications have warned of these failures, the scientific community remains mostly unaware, and there is a need to focus their efforts on potential therapeutics that can slow or halt development of the disease. Clinical Studies and Therapies in Parkinson’s Disease: Translations from Preclinical Models analyzes preclinical models based on exogenous neurotoxins and why they have failed. Neuroscientists, neurologists, and neuropharmacologists will benefit greatly from the book’s discussion of these newer models, their benefits, and the need for their implementation. This book also provides the basic concepts of dopamine metabolism for students taking courses in neurochemistry, neuroscience, neuropharmacology, biochemistry, and medicine. Reviews Parkinson's disease classification, pharmacological therapies, and nonmotor and motor symptoms Analyzes preclinical models of Parkinson’s disease therapies based on exogenous neurotoxins and why they have failed Reviews genetic preclinical models based on genetic mutations and endogenous neurotoxins Proposes a more physiological model directly related to the metabolism of dopaminergic neurons Provides the basic concepts and mechanisms of dopamine metabolism

Clinical Studies and Therapies in Parkinson s Disease

More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson’s disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4–6 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for

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Clinical Studies and Therapies in Parkinson s Disease

More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson's disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4-6 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for

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Clinical Trials In Parkinson s Disease

Download or read online Clinical Trials In Parkinson s Disease written by Santiago Perez-Lloret, published by Unknown which was released on 2021. Get Clinical Trials In Parkinson s Disease Books now! Available in PDF, ePub and Kindle.

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Towards New Therapies for Parkinson s Disease

Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in

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Therapeutics of Parkinson s Disease and Other Movement Disorders

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Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for

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In this exciting and timely book new approaches to repairing the parkinsonian brain are described by leading experts. Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. This book gives an overview of the current state-of-the-art research for brain repair,

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