Epigenetics in Organ Specific Disorders

This book PDF is perfect for those who love Medical genre, written by Anonim and published by Elsevier which was released on 15 November 2022 with total hardcover pages 666. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Epigenetics in Organ Specific Disorders books below.

Epigenetics in Organ Specific Disorders
Author : Anonim
File Size : 46,9 Mb
Publisher : Elsevier
Language : English
Release Date : 15 November 2022
ISBN : 9780128239315
Pages : 666 pages
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Epigenetics in Organ Specific Disorders by Anonim Book PDF Summary

Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth. Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies. Identifies unique epigenetic mechanisms that occur in normal and disease conditions in each organ, examining differences and similarities Explores organ specific epigenetic mechanisms to enable drug discovery and development Features chapter contributions from leading researchers in the field

Epigenetics in Organ Specific Disorders

Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare

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In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA

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