Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC

This book PDF is perfect for those who love Science genre, written by Anthony Faber and published by Academic Press which was released on 30 January 2023 with total hardcover pages 150. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC books below.

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC
Author : Anthony Faber
File Size : 49,6 Mb
Publisher : Academic Press
Language : English
Release Date : 30 January 2023
ISBN : 9780128228340
Pages : 150 pages
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Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC by Anthony Faber Book PDF Summary

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer. Presents historical context on how NSCLC and SCLC has been treated, with an emphasis on NSCLC and how the concept of EGFR inhibitors has been implemented Discusses critical resistant mechanisms seen in the clinic to 1st, 2nd and 3rd generation EGFR inhibitors Encompasses the current state of affairs in clinical trials to address resistance

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often

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The treatment of patients with advanced malignancies has undergone remarkable change in the last few years. While in the past decisions about systemic therapy were largely based on the performance status of a patient, oncologists today also take into account the pathological and molecular characteristics of the patient’s tumor.

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