Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

This book PDF is perfect for those who love Medical genre, written by Heba Mohamed Mansour and published by Elsevier which was released on 06 June 2023 with total hardcover pages 606. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders books below.

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders
Author : Heba Mohamed Mansour
File Size : 47,8 Mb
Publisher : Elsevier
Language : English
Release Date : 06 June 2023
ISBN : 9780443186783
Pages : 606 pages
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Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders by Heba Mohamed Mansour Book PDF Summary

Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders. Provides a thorough overview of RTKs biology and their role in health and disease progression and modulation Highlights RTK families and the numerous receptors within each subfamily Examines RTKIs and other protein kinase inhibitors in pre-clinical and clinical trials in both neurodegenerative and psychiatric disorders Gives future directions of possible safe effective targeted RTKIs and other protein kinase inhibitors that may be repositioned in various neurodegenerative and psychiatric disorders Includes chapter contributions from renowned experts in biology, pharmacology, neurology, psychiatry, and oncology

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and

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