Author | : Roger J. W. Truscott |
File Size | : 54,8 Mb |
Publisher | : John Wiley & Sons |
Language | : English |
Release Date | : 12 February 2021 |
ISBN | : 9783527826735 |
Pages | : 224 pages |
Long lived Proteins in Human Aging and Disease by Roger J. W. Truscott Book PDF Summary
This authoritative overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed.