OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay
OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay
Author : OECD
File Size : 45,6 Mb
Publisher : OECD Publishing
Language : English
Release Date : 23 October 1986
ISBN : 9789264071407
Pages : 5 pages
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OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay by OECD Book PDF Summary

This assay may be used to measure gene mutation in yeast, a eukaryotic micro-organism. Strains of Saccharomyces cerevisiae have been developed which detect forward or reverse mutations. A variety of haploid and diploid strains of the yeast can be ...

OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay

OECD Guidelines for the Testing of Chemicals Section 4 Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay by OECD

This assay may be used to measure gene mutation in yeast, a eukaryotic micro-organism. Strains of Saccharomyces cerevisiae have been developed which detect forward or reverse mutations. A variety of haploid and diploid strains of the yeast can be ...

Get Book
OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay

OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 480 Genetic Toxicology Saccharomyces cerevisiae Gene Mutation Assay by OECD

This assay may be used to measure gene mutation in yeast, a eukaryotic micro-organism. Strains of Saccharomyces cerevisiae have been developed which detect forward or reverse mutations. A variety of haploid and diploid strains of the yeast can be ...

Get Book
OECD Guidelines for the Testing of Chemicals Section 4 Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay

OECD Guidelines for the Testing of Chemicals Section 4 Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay by OECD

This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...

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OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay

OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay by OECD

This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 477 Genetic Toxicology Sex Linked Recessive Lethal Test in Drosophila melanogaster

OECD Guidelines for the Testing of Chemicals Section 4 Test No 477 Genetic Toxicology Sex Linked Recessive Lethal Test in Drosophila melanogaster by OECD

Mutations in the X-chromosome of Drosophila melanogaster are phenotypically expressed in males carrying the mutant gene. When the mutation is lethal in the hemizygous condition, its presence is inferred from the absence of one class of male ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 485 Genetic toxicology Mouse Heritable Translocation Assay

OECD Guidelines for the Testing of Chemicals Section 4 Test No 485 Genetic toxicology Mouse Heritable Translocation Assay by OECD

The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The types of chromosome changes detected in this test system are reciprocal translocations ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 488 Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays

OECD Guidelines for the Testing of Chemicals Section 4 Test No 488 Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays by OECD

This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations in somatic and germ cells. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The transgenes contain reporter genes for the detection

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 479 Genetic Toxicology In vitro Sister Chromatid Exchange Assay in Mammalian Cells

OECD Guidelines for the Testing of Chemicals Section 4 Test No 479 Genetic Toxicology In vitro Sister Chromatid Exchange Assay in Mammalian Cells by OECD

The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...

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