Transgenic Models in Pharmacology

This book PDF is perfect for those who love Medical genre, written by Lutz Hein and published by Springer Science & Business Media which was released on 06 December 2012 with total hardcover pages 280. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Transgenic Models in Pharmacology books below.

Transgenic Models in Pharmacology

Author	: Lutz Hein
File Size	: 47,6 Mb
Publisher	: Springer Science & Business Media
Language	: English
Release Date	: 06 December 2012
ISBN	: 9783642189340
Pages	: 280 pages

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Transgenic Models in Pharmacology by Lutz Hein Book PDF Summary

Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.

Transgenic Models in Pharmacology by Lutz Hein

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Welfare Aspects of Transgenic Animals by L.F.M. van Zutphen,Miriam van der Meer

v Preface The quality of animal models used in biomedical research has increased substantially since the first successful microinjection of foreign DNA frag ments into a mouse zygote in the early 1980s. New well-defined animal models, developed either by micro injection techniques or by homologous recombination in embryonic stem (ES)

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Mouse Models for Drug Discovery Methods and Protocols by Gabriele Proetzel,Michael V. Wiles

With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. Herein, these models are applied to a wide field of disease areas, including diabetes, cardiovascular disease, skin disorders, cancer, neurodegenerative and neuromuscular

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Transgenic Models in Medicine and Agriculture by Robert B. Church

This text goes beyond the traditional mouse model to examine the transfer of genetic material in a wide range of species including pigs, sheep, chickens and several species of fish. The work explains how animal transgenesis is being employed as a model for human diseases, describing innovative programs for domestic

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Transgenic Animal Technology by Carl A. Pinkert

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer — from molecular methods to whole animal considerations — for important laboratory and domestic animal species. It describes methodologies

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Methods of Behavior Analysis in Neuroscience by Jerry J. Buccafusco

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the

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Care Use and Welfare of Marmosets as Animal Models for Gene Editing Based Biomedical Research by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly

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Animal Biotechnology by Ashish Verma,Anchal Singh

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering,

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