Protein Quality Control in Neurodegenerative Diseases

This book PDF is perfect for those who love Medical genre, written by Richard I. Morimoto and published by Springer Science & Business Media which was released on 13 December 2012 with total hardcover pages 145. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Protein Quality Control in Neurodegenerative Diseases books below.

Protein Quality Control in Neurodegenerative Diseases

Author	: Richard I. Morimoto
File Size	: 42,9 Mb
Publisher	: Springer Science & Business Media
Language	: English
Release Date	: 13 December 2012
ISBN	: 9783642279287
Pages	: 145 pages

Get Book

Protein Quality Control in Neurodegenerative Diseases by Richard I. Morimoto Book PDF Summary

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

Protein Quality Control in Neurodegenerative Diseases by Richard I. Morimoto,Yves Christen

Get Book

Quality Control of Cellular Protein in Neurodegenerative Disorders by Uddin, Md. Sahab,Ashraf, Ghulam Md.

Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of

Get Book

Protein Quality Control in Neurodegenerative Diseases by Richard I. Morimoto,Yves Christen

Get Book

The Molecular and Cellular Basis of Neurodegenerative Diseases by Michael S. Wolfe

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters

Get Book

Molecular Chaperones and Neurodegeneration by Cintia Roodveldt,Tiago F. Outeiro,Janice E. Braun

Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many

Get Book

Fundamentals of Neurodegeneration and Protein Misfolding Disorders by Martin Beckerman

This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on

Get Book

Protein Misfolding and Disease by Peter Bross,Niels Gregersen

For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that protein folding to the functional conformations as well as the structural maintenance of protein molecules are very complex processes has only emerged during the last ten years. The

Get Book

The Proteasome in Neurodegeneration by Leonidas Stefanis,J. N. Keller

In the last 50 years a wealth of information has allowed us to understand the contribution of various regulatory factors that alter mRNA and protein s- thesis to a variety of physiological and pathological conditions. However, such regulation is only one of many factors that contribute to the levels of a

Get Book