OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro
OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro
Author : OECD
File Size : 49,6 Mb
Publisher : OECD Publishing
Language : English
Release Date : 23 October 1986
ISBN : 9789264071445
Pages : 7 pages
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OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro by OECD Book PDF Summary

The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...

OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro

OECD Guidelines for the Testing of Chemicals Section 4 Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro by OECD

The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...

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OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro

OECD Guidelines for the Testing of Chemicals Section 4 Health Effects Test No 482 Genetic Toxicology DNA Damage and Repair Unscheduled DNA Synthesis in Mammalian Cells in vitro by OECD

The Test Guideline for Unscheduled DNA Synthesis (UDS) in mammalian cells in vitro describes procedures utilizing primary cultures, human lymphocytes or established cell lines, to detect DNA repair synthesis after excision and removal of a stretch ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 486 Unscheduled DNA Synthesis UDS Test with Mammalian Liver Cells in vivo

OECD Guidelines for the Testing of Chemicals Section 4 Test No 486 Unscheduled DNA Synthesis UDS Test with Mammalian Liver Cells in vivo by OECD

The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage induced by chemical substances ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 479 Genetic Toxicology In vitro Sister Chromatid Exchange Assay in Mammalian Cells

OECD Guidelines for the Testing of Chemicals Section 4 Test No 479 Genetic Toxicology In vitro Sister Chromatid Exchange Assay in Mammalian Cells by OECD

The sister chromatid exchange (SCE) assay is a short-term test for the detection of reciprocal exchanges of DNA between two sister chromatids of a duplicating chromosome. Detection of SCEs requires some means of differentially labeling sister ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 487 In Vitro Mammalian Cell Micronucleus Test

OECD Guidelines for the Testing of Chemicals Section 4 Test No 487 In Vitro Mammalian Cell Micronucleus Test by OECD

The in vitro micronucleus test is a genotoxicity test for the detection of micronuclei in the cytoplasm of interphase cells.

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Test No 489 In Vivo Mammalian Alkaline Comet Assay

Test No 489 In Vivo Mammalian Alkaline Comet Assay by OECD

The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 485 Genetic toxicology Mouse Heritable Translocation Assay

OECD Guidelines for the Testing of Chemicals Section 4 Test No 485 Genetic toxicology Mouse Heritable Translocation Assay by OECD

The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The types of chromosome changes detected in this test system are reciprocal translocations ...

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OECD Guidelines for the Testing of Chemicals Section 4 Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay

OECD Guidelines for the Testing of Chemicals Section 4 Test No 481 Genetic Toxicology Saacharomyces cerevisiae Miotic Recombination Assay by OECD

This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...

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