Telomeres and Telomerase in Cancer

This book PDF is perfect for those who love Medical genre, written by Keiko Hiyama and published by Springer Science & Business Media which was released on 18 March 2009 with total hardcover pages 380. You could read this book directly on your devices with pdf, epub and kindle format, check detail and related Telomeres and Telomerase in Cancer books below.

Telomeres and Telomerase in Cancer
Telomeres and Telomerase in Cancer
Author : Keiko Hiyama
File Size : 50,5 Mb
Publisher : Springer Science & Business Media
Language : English
Release Date : 18 March 2009
ISBN : 9781603278799
Pages : 380 pages
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Telomeres and Telomerase in Cancer by Keiko Hiyama Book PDF Summary

Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.

Telomeres and Telomerase in Cancer

Telomeres and Telomerase in Cancer by Keiko Hiyama

Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved

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Telomeres and Telomerase in Aging Disease and Cancer

Telomeres and Telomerase in Aging Disease and Cancer by K. Lenhard Rudolph

Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular

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Telomeres and Telomerase

Telomeres and Telomerase by Predrag Slijepcevic

Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play

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Telomerase Inhibition

Telomerase Inhibition by Lucy Andrews,Trygve O. Tollefsbol

This volume presents a compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition. The techniques described provide the researcher with a diverse and comprehensive set of tools for the study of telomerase inhibition. The volume is aimed at biochemists, molecular biologists, cancer

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Neuroblastoma

Neuroblastoma by Chandrika Gowda

Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive

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Telomerases Telomeres and Cancer

Telomerases Telomeres and Cancer by Guido Krupp,Reza Parwaresch

This volume provides broad insights to the most recent discoveries in telomere biology, with current applications in tumor diagnostics and future potentials in therapy. Special features of diverse organisms are presented, with ciliates, the "telomerase discoverer organisms"; yeasts, the "molecular genetisists' toy for eukaryotes"; including plants and insects as well. 28

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Telomere

Telomere by Marcelo Larramendy

This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability,

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Telomere Territory and Cancer

Telomere Territory and Cancer by Parvin Mehdipour

Timing, racing, combating, struggling and targeting are some actions through which cellular fate could be reflected and evaluated. Interaction between cell territory and environment occur during pre-embryonic, fetal development, and post-natal periods. What the researchers observe as the outcome of telomeres behavior is only the peak of an ice mountain

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